Formulation, Optimization and Characterization of Novel Modified Release Gel Formulation of Dexibuprofen Using Full Factorial Design
نویسندگان
چکیده
منابع مشابه
Formulation of Topical Bioadhesive Gel of Aceclofenac Using 3-Level Factorial Design
The objective of this work was to develop bioadhesive topical gel of Aceclofenac with the help of response-surface approach. Experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of Poloxamer 407 (PL-407 = X1) and hydroxypropylmethyl cellulose K100 M (HPMC = X2)] on the bioadhesive character of gel, rheological property o...
متن کاملFormulation of Topical Bioadhesive Gel of Aceclofenac Using 3-Level Factorial Design
The objective of this work was to develop bioadhesive topical gel of Aceclofenac with the help of response-surface approach. Experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of Poloxamer 407 (PL-407 = X1) and hydroxypropylmethyl cellulose K100 M (HPMC = X2)] on the bioadhesive character of gel, rheological property o...
متن کاملFormulation and Evaluation of Sustained Release Pellets of Tramadol HCl Using 3 Full Factorial Design
The present research concerns the formulation and evaluation of sustained release pellets filled capsule of opioid analgesic, Tramadol HCl. Development of sustained release dosage form is to maintain therapeutic blood levels of the drug for extended period of time. Sustained release formulation provides uniform concentration at absorption site, maintains plasma concentration within a therapeuti...
متن کاملFormulation and Optimization of Clotrimazole-Loaded Proniosomal Gel Using 32 Factorial Design
The main aim of the study was to develop and statistically optimize the proniosomal gel for enhanced transdermal delivery using 3(2) factorial designs to investigate the influence of both non-ionic surfactant and cholesterol to maximize the entrapment efficiency and flux. The concentration of non-ionic surfactant and cholesterol were taken as independent variables, while entrapment efficiency a...
متن کاملFormulation and Characterization of Solid Dispersions of Glimepiride through Factorial Design
In order to enhance in vitro dissolution and content uniformity of poorly soluble drug glimepiride by preparing solid dispersions using modified solvent fusion method, solid dispersions of drug were prepared by modified fusion solvent method using PEG 6000 and PVP K25 (as carrier). Eight batches (F1-F8) were prepared by Factorial design (23) by taking three ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of pharma and Bio Sciences
سال: 2020
ISSN: 0975-6299
DOI: 10.22376/ijpbs/lpr.2020.10.5.p178-190